MODULAR DESIGN OF BI- AND MULTI-SPECIFIC KNOB DOMAIN FUSIONS

Modular design of bi- and multi-specific knob domain fusions

IntroductionThe therapeutic potential of bispecific antibodies is becoming widely recognised, with over a hundred formats already described.For many applications, enhanced tissue penetration is sought, so bispecifics with low molecular weight may offer a route to enhanced potency.Here we report the design of bi- and tri-specific antibody-based cons

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Determinants of consistent condom use among Filipino women: Results from the 2017 Philippine National Demographic and Health Survey

Abstract Background Consistent condom use in women, defined as the self-reported usage of male condom in every sexual encounter of the respondent with her most recent partner in the last 12 months, had been perennially low in the Philippines.This is despite consistent condom use being a tested Rear View Camera and proven public health intervention

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Determinative Variables Toward Promoting Use of Active Modes of Transportation: Enhancing Level of Sustainable Mobility in Communities

Most current transportation Hockey Protective - Elbow Pads - Senior systems around the world are cause for pressing concern and a menace to sustainability of social justice, and economic and environmental vitality.From a universal agreement that transportation needs an urgent alteration in travel modes, policies, planning, and behaviors through to

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